Multiple medications increase the risk of depression

A new study in the United States says that more than a third of American adults may be using prescription drugs that cause depression or increase the risk of suicide, and they know nothing about these risks. Researchers published a paper in the Journal of the American Medical Association warned that multiple medications increase the risk of depression and require medical personnel and patients to pay high attention.

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The study was completed in collaboration with researchers at the University of Illinois at Chicago and Columbia University. They retrospectively analyzed the drug use patterns of more than 26,000 American adults from 2005 to 2014 and found over 200 commonly used prescription drugs, including hormonal contraceptives, antihypertensives, heart drugs, proton pump inhibitors, antacids, and analgesics. Drugs, etc., have potential side effects that lead to depression or suicidal tendency. If these drugs are taken at the same time, that is, multiple medications, the risk of depression or even suicide can be greatly increased.

Researchers say that many people who take daily prescription drugs unrelated to depression have depression symptoms and are diagnosed with depression, which is likely to be the result of multiple medications. Research data show that about 15% of adults who take three or more of these drugs at the same time have depressive symptoms, compared with the proportion of people who do not take any drug. Only 5%, 7% were taking one drug, and 9% were taking both drugs.

Researchers point out that in the United States, depression is one of the major causes of disability and suicide. Eliminating or reducing depression should be regarded as an important public health issue. New research shows that even if it is commonly used prescription drugs, multiple medications may lead to depression. In recent years, the use of prescription drugs in the United States may lead to an increased risk of depression, but drug users know nothing about these risks. In response to this situation, the researchers suggest that on the one hand, studies on the interactions between drugs should be strengthened, and depression should be considered as a potential drug risk in the scope of research; on the other hand, a strict drug safety system should be used to urge the medical staff to guide patients. Pay attention to the risk of multiple medications when administering medications.

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