In the age of “national calcium supplement”, many people take calcium supplements every day. However, some people have little effect, and the symptoms such as leg pain and cramps have not been alleviated. The reason is that the deficiency of active osteocalcin caused by vitamin K2 deficiency in vivo is also a cause. Recently, held in Beijing “seize the key vitamins, calcium and more effective” expert salon activity, Peking University third hospital, deputy director of orthopaedic Song Chun, vice President of the vitamin K2 power science calcium related topics to discuss.
Vitamin K2 is a unique vitamin. It is made from a number of bacteria in the gut microbes that can go directly through the walls of the blood vessel into the bones and tissues and play a variety of roles in the body. Among them, the most outstanding is to help calcium to become bone.
Song stressed that vitamin K2 has a primary osteocalcin, which helps osteoblasts secrete, and becomes active osteocalcin, which promotes calcium deposition in the blood. If there is sufficient vitamin K2 in the body, it can activate osteocalcin, and the activated osteocalcin has a unique affinity for calcium ions, which can lead calcium into bone and calcium salt deposit, thus promoting bone mineralization. Vitamin K2 and vitamin D3 cooperation, can effectively promote calcium absorption and calcium osteogenesis, is the double guarantee of calcium supplement. Vitamin K2, on the other hand, not only can promote bone cells, improve its activity, also can inhibit the activity of osteoclast, promoting osteoclast apoptosis, inhibiting bone resorption, have the effect of reducing bone loss.
Vitamin K2 deficiency in the body, calcium supplements not only can not play a role, but also leave health risks. Calcium ions that enter the bloodstream through the gut cannot be converted into bone calcium, and can be deposited in an ecotone. Once deposited in the articular cartilage, blood vessels, kidneys, skin and other tissues and organs, the calcium can lead to calcification of the articular cartilage, osteogenic pain, osteoarthritis, and vascular sclerosis. Studies have found that vitamin K2 to intelligent adjusting calcium deposition, prevent soft tissue and vascular calcification, the hardening of the arteries, high blood pressure, bone and joint pathological changes, and Parkinson’s disease has an irreplaceable role of and repair inhibition.
Vitamin K2 is found in fermented foods such as natto, pickles and some cheese. However, this kind of food is generally lacking in the daily diet of Chinese people, so there is insufficient vitamin K2 in the diet structure of our population. The 2013 edition of the handbook for prevention and treatment of osteoporosis in China recommended that the daily vitamin K2 intake for healthy adults should be 50 to 120 micrograms, in order to maintain bone health and prevent osteoporosis. Vitamin K2 supplementation in osteoporosis and bone subhealthy population should be increased in a moderate amount. A number of clinical studies have confirmed that vitamin K2 supplementation can effectively maintain the bone mineral density and prevent fractures in women of reproductive age, and can significantly reduce the bone density caused by age growth.