What is a test-tube baby, the principle of a test-tube baby?

What is a test-tube baby? 

IVF babies are commonly referred to as IVF-ETs, commonly known as IVF-ETs, in which eggs are taken from a woman’s ovary, fertilized with sperm in vitro and cultured for 3 to 5 days, and then transferred to the uterine cavity to develop to the stage of egg division or blastocyst. The whole process of developing a fetus. Babies produced by in vitro fertilization are called test-tube babies, which also grow in the mother’s womb. 

The world’s first test-tube baby was born in Britain in 1978, while the first “test-tube baby” in China was born in Beijing in 1988. IVF technology can help infertile couples who are still unable to conceive after conventional treatment to have babies. 


IVF principle. 

“IVF” is not a real baby growing up in a test tube, but a couple of eggs are taken from the ovary, and in the lab they bind to the sperm of the man, form the embryo, and transfer the embryo into the womb. Make it in the mother’s uterus implantation, pregnancy. Normal pregnancy requires sperm and eggs to meet in the fallopian tube, the two combine to form fertilized eggs, then fertilized eggs back to the uterine cavity, continue pregnancy. Studies show that the pregnancy rate is about 40% after a cycle of treatment, with a slightly lower birth rate. 

History of IVF. 

The world’s first test-tube baby was born in Britain in 1978. It was the result of a joint study by Dr. steptoe and Professor Edowrds. Professor Edowrds, known as the miracle in the history of human medicine, was awarded the Nobel Prize in medicine in 2010. IVF usually puts eggs in the same medium and allows them to combine naturally, known as conventional fertilization. But sometimes fertilization fails for a variety of reasons. 

In 1992, Palermo, a Belgian doctor, successfully applied intracytoplasmic sperm injection (ICSI) to humans. This technique can solve the problem of failure of conventional fertilization, thus increasing the success rate of IVF. ICSI is a milestone in the treatment of severe oligozoospermia and male infertility requiring testicular sperm extraction. 

In recent years, many IVF centers have developed a diagnosis of preimplantation genetic diseases. For couples with some special chromosomal abnormalities or hereditary diseases, normal embryos can be selected by PGD technique to obtain healthy self-generation. 

Embryos are screened for multiple chromosomes to find normal embryos that can be transferred, a technique called PGS, which has been used in clinical practice in recent years. 

Who can be a test-tube baby? 

1. Patients with fallopian tube obstruction; 

2. The patients with unexplained infertility could not be pregnant by IUI treatment. 

(3) severe oligozoospermia, or azoospermia, which requires spermatozoa to be obtained by testicular or epididymal puncture; 

4. Women with endometriosis and infertility can use IVF to help pregnancy. 

5. The patients with ovulation disorder, after the general ovulation promotion treatment, no mature follicle growth.

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