The death rate of the Ebola haemorrhagic Fever (Huayi), which caused severe outbreaks in West Africa, was high, but some patients survived. An international collaborative study led by Japanese researchers has found some biomarkers in the blood of patients who died from Ebola haemorrhagic fever, which will help quickly identify and treat severe patients.
Yoshihiro Kawaoka, a professor of medical science at the University of Tokyo, Japan, reported in a new issue of the American academic journal Cell hosts and parasites that their international research team had conducted an investigation in Sierra Leone, a West African country prevalent in Ebola haemorrhagic fever, from 2013 to 2016, The blood samples of 20 patients and 10 healthy people were sampled, with 9 of the 20 patients eventually dying and 11 surviving.
The results showed that the immune system in the patients with death had abnormal reaction and caused the dysfunction of tissue. Compared with the rehabilitation patients, the death of the blood of the pancreatic enzymes in the amount of about 30 times times, and the general situation of pancreatic enzymes mainly in the pancreas. In addition, the amount of one protein in the blood of the deceased patient is only one-fourth to half that of the recovering patient. The researchers believe that these biomarkers in the blood can help identify patients with severe illness as early as possible.
The study team found that the study revealed part of the mechanism for the severe outbreak of Ebola haemorrhagic fever, which could help develop more effective public health responses in the event of Ebola haemorrhagic fever.